Post-Ictal Heart Rate Oscillations in Partial Epilepsy: Data and Analysis

This database is described in

Al-Aweel IC, Krishnamurthy KB, Hausdorff JM, Mietus JE, Ives JR, Blum AS, Schomer DL, Goldberger AL. Post-Ictal Heart Rate Oscillations in Partial Epilepsy. Neurology 53(7):1590-1592 (1999 October 22).

Please cite this publication when referencing this material, and also include the standard citation for PhysioNet:

Goldberger AL, Amaral LAN, Glass L, Hausdorff JM, Ivanov PCh, Mark RG, Mietus JE, Moody GB, Peng C-K, Stanley HE. PhysioBank, PhysioToolkit, and PhysioNet: Components of a New Research Resource for Complex Physiologic Signals. Circulation 101(23):e215-e220 [Circulation Electronic Pages;]; 2000 (June 13).
sample waveform

The authors of the first reference above report “post-ictal heart rate oscillations in a heterogeneous group of patients with partial epilepsy. This pattern is marked by the appearance of transient but prominent low-frequency heart rate oscillations (0.01 - 0.1 Hz) immediately following five of 11 seizures recorded in five patients. This finding may be a marker of neuroautonomic instability, and, therefore, may have implications for understanding perturbations of heart rate control associated with partial seizures.”

The annotated ECG recordings on which this study was based may be downloaded from this page. Each recording consists of a (text) header file (with suffix .hea), a (binary) signal file (with suffix .dat), and a (binary) annotation file (with suffix .ari); these files may be read using the WFDB software package. The text file times.seize indicates the intervals of the seizure in each recording, based on simultaneously recorded EEGs (not available).