Generalized Multiscale Entropy Analysis

Our new website is in development. Try it out at: and give us feedback

The method of generalized multiscale entropy (GMSE) analysis is useful for investigating complexity in physiologic signals and other series that have correlations at multiple (time) scales. It represents a generalization of the original method of multiscale entropy analysis.

A tutorial about generalized multiscale entropy analysis is available here (a PDF version is also available). It discusses various methods for calculating a coarse-grained time series, and the impact of this choice on the multiscale entropy calculation. The results are illustrated using simulated data as well as real inter-beat interval data from PhysioBank.

The software described in the tutorial is here.

Questions and Comments

If you would like help understanding, using, or downloading content, please see our Frequently Asked Questions.

If you have any comments, feedback, or particular questions regarding this page, please send them to the webmaster.

Comments and issues can also be raised on PhysioNet's GitHub page.

Updated Friday, 1 February 2019 at 17:03 BRST

PhysioNet is supported by the National Institute of General Medical Sciences (NIGMS) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under NIH grant number 2R01GM104987-09.